In this report we introduce a framework to tackle toxicogenomics problems: i.e., how to control the toxic risk while manipulating genes structures.
It is a first step towards a more systematic study on how safety properties can be guaranteed by newly biosynthesized components. This way, not only we could provide new structures that  answer to  specific needs but also they could be safely used requiring less time-consuming and costly testing to rule out undesired effects.

We propose an extension to reaction systems that takes into consideration time. We model it through Petri nets with causal time and we discuss how to use the encoding to address toxicogenomics problems.
